Anavex Life Sciences, a clinical-stage biopharmaceutical
company, has announced encouraging findings from its 48-week Phase 2 extension
study, focusing on Parkinson’s disease dementia. The study indicates that
ANAVEX®2-73 (blarcamesine) shows significant clinical benefits, achieving both
its primary and secondary objectives.
The clinical trial evaluated the safety, tolerability, and efficacy of ANAVEX®2-73 over a
prolonged period. Patients displayed consistent improvements in all efficacy
endpoints, including the Movement Disorder Society-Unified Parkinson’s Disease
Rating Scale (MDS-UPDRS) and the Clinical Global Impression – Improvement
(CGI-I) scale. These results suggest a potential breakthrough in the long-term
management of Parkinson’s disease symptoms.
Christopher U Missling, PhD, President & CEO of Anavex, expressed optimism about the findings, noting
the drug’s potential to address the urgent, unmet needs of Parkinson’s
patients. The data demonstrated not only symptom management but also hints at
the possibility of slowing or reversing disease progression, a significant advancement
over current treatments that primarily focus on symptom relief.
The study also allowed patients to continue their usual anti-Parkinson’s medications,
reinforcing the potential versatility of ANAVEX®2-73 in real-world scenarios.
These promising results have propelled Anavex to plan a pivotal trial, aiming
to further validate these findings and bring ANAVEX®2-73 closer to market.
Anavex continues to explore the capabilities of ANAVEX®2-73 in treating various neurodegenerative and
neurodevelopmental disorders, including Alzheimer’s disease and Rett syndrome.
Their commitment to advancing medical science and improving patient outcomes remains steadfast.
The Michael J. Fox Foundation has recognized Anavex’s efforts, awarding research grants to support
ongoing and future studies. This partnership underscores the potential impact
of ANAVEX®2-73 on the broader field of neurodegenerative disease treatment.
For more information, visit the Anavex Life Sciences website and follow their updates on
social media platforms.
Visit this page on LinkedIn, to learn more.
More about Anavex on https://www.biospace.com/article/releases/anavex-life-sciences-initiates-placebo-controlled-u-s-phase-2-clinical-trial-of-anavex-3-71-in-schizophrenia/